The Gary Null Show - 04.04.22

A prune—or six—a day may keep inflammation at bay   Pennsylvania State University, April 1, 2022   A study in postmenopausal people suggests eating nutrient-rich prunes every day may be beneficial to bone health, reducing inflammatory factors that contribute to osteoporosis. Previous research has shown that polyphenol extracts—plant compounds that act as antioxidants and reduce inflammation—in prunes promote lower levels of oxidative stress and inflammation in a type of bone cell called osteoclasts. In a new study, researchers explored the effects of prunes on bone health after menopause. Postmenopausal women with a bone mineral density score that was defined as low—a marker of osteoporosis—were divided into three groups: One group ate 50 grams (g) of prunes (about six prunes) daily for 12 months. A second group ate 100 g of prunes (about 12 prunes) daily for 12 months. A control group ate no prunes.   (NEXT)   Cardamonin shows promise for treating aggressive breast cancer   Study shows that compound from cardamom spice can kill triple-negative breast cancer cells    Florida A&M University, April 3, 2022   Cardamonin — a natural compound found in the spice cardamom and other plants — could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells. The findings also show that the compound targets a gene that helps cancer cells elude the immune system. About 10-15% of breast cancers are triple-negative, which means they don’t have receptors for estrogen or progesterone and don’t make excess amounts of a protein called HER2. These tumors are difficult to treat because they don’t respond to the hormone-based therapies used for other types of breast cancer. They also tend to be more aggressive and have a higher mortality rate than other breast cancers.   (NEXT)   Mineral supplement could stop fatty liver disease progression   University of Michiganm April 3, 2022   Results from a preclinical study add new evidence that a multi-mineral dietary supplement known as Aquamin could be a simple and effective way to reduce the long-term health consequences of non-alcoholic fatty liver disease. Aquamin, which is derived from calcified red marine algae, is rich in calcium, magnesium and 72 other minerals and trace elements. Most people living in Western society do not meet the USDA daily intake guidelines for the intake of calcium and magnesium and, presumably, other minerals nutritionally associated with these minerals. In preliminary studies, the researchers fed mice a high-fat diet to induce the development of non-alcoholic fatty liver disease and NASH. They studied these mice for 15 to 18 months to observe the full spectrum of liver disease, including advanced fibrotic changes and liver cancer.   (NEXT)   Half of older adults now die with a dementia diagnosis, up sharply from two decades ago   University of Michigan, April 2, 2022   Nearly half of all older adults now die with a diagnosis of dementia listed on their medical record, up 36% from two decades ago, a new study shows. The study, published in JAMA Health Forum by a University of Michigan team, uses data from 3.5 million people over the age of 67 who died between 2004 and 2017. It focuses on the bills their providers submitted to the traditional Medicare system in the last two years of the patients' lives. In 2004, about 35% of these end-of-life billing claims contained at least one mention of dementia, but by 2017 it had risen to more than 47%. Even when the researchers narrowed it down to the patients who had at least two medical claims mentioning dementia, 39% of the patients qualified, up from 25% in 2004.