Eleanor G. Rogan, PhD: Estrogen Metabolism, Tumor Initiation and Cancer
Eleanor Rogan has been involved in ground breaking research that has helped uncover a preventable cause of cancer development related to unbalanced estrogen metabolism. Her early work on tumor initiation by catechol quinones of estrogens established a unified mechanism for the development of breast, prostate and other human cancers. This work has recently resulted in tests that will help with early detection, and chemoprevention with natural substances such as resveratrol, n-acetylcystiene and functional medicine-based clinical interventions. Further reading: Cavalieri E, & Rogan E. The molecular etiology and prevention of estrogen-initiated cancers. Mol. Aspects Med., 36:1-55, 2014. Muran PJ, Muran SY, Beseler CL, et al. Breast health and reducing breast cancer risk: a functional medicine approach. J Altern Complement Med. 2015 Jun;21(6):321-6.